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Proteinuria may represent a benign pathology in asymptomatic patients, or it can be a sign of significant renal or systemic disease. The latter is usually associated with persistent proteinuria or other clinical findings such as renal failure.

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This article will focus on the mechanisms, causes and diagnostic approach of proteinuria. Giant cell myocarditis is a rare condition first described in It has a reported incidence range from 0. It affects female and male individuals, equally, and usually occurs in young and middle-aged persons.

The underlying aetiology of giant cell myocarditis is unknown but it is thought to be mediated by T-lymphocytes.


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Diagnosis is made via histological examination of myocardial tissue and is characterized by a mixed inflammatory cell infiltrate with multinucleated giant cells and cardiomyocyte necrosis, predominantly affecting the ventricles. The following report describes a rare case of giant cell myocarditis in a year-old man with a history of hypertension and heart failure, who died while waiting to be seen in the emergency department. Autopsy findings revealed an enlarged, dilated heart with histologic features in keeping with giant cell myocarditis, along with features of heart failure.

Diagnosis of giant cell myocarditis is less common in the elderly age group, possibly due to a less severe disease process in this age group and it may be misdiagnosed because older individuals may have other cardiovascular diseases CVDs. The purpose of this study was to investigate the different combination of testcrosses for morphological and yield relating traits and to investigate general combining ability of the inbred lines. Line x-tester analysis was used to test general combining ability GCA effects of 24 S4 lines of sweet corn.

Alpha lattice design with two replications and two checks was used during the experiment. Research data were recorded on various flowering, morphological and yield parameters. Highly significant variations were recorded among the testcrosses for the studied traits except anthesis silking interval ASI , kernel weight.

Minimum days to tasseling days and silking GCA effect was Maximum value 3. Lowest plant height Maximum cob length For cob length GCA effect of 1. Maximum kernel weight GCA effect of 1. Highest mean GCA effect for grain yield was found to be Generally a low GCA value, either positive or negative indicates that the mean of a parent does not largely vary from its offsprings.

In contrast, high GCA value suggests that parent is either superior or inferior to the general mean and it has high heritability and less environmental effects. Based on the findings in this research, the above mentioned testcrosses can be included in future sweet corn breeding programs where early flowering and yield attributes is desired.

Internet addiction is a major health concern among undergraduate students; however, few studies have addressed modifiable behavioural factors associated with internet addiction in the context of Taiwan.


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This study aimed to investigate associations between physical activity and the risk of internet addiction among undergraduate students in Taiwan. In , we recruited undergraduate students from Northern Taiwan to participate in a cross-sectional questionnaire-based survey. For the surveyed students, the average CIAS score was No significant associations were observed between internet addiction and 75 min of VPA or min of total physical activity per week.

Among the 5 dimensions of the CIAS scale, MPA was negatively associated with tolerance symptoms, time-management problems, and interpersonal and health-related problems when a routine of min per week was adopted. A routine of min of MPA per week was associated with a lower risk for internet addiction. We also recommend longitudinal research on the effects of engaging in physical activity on the risk of internet addition. The coronavirus disease COVID emergency has clearly shown the need to discover, test and produce a new vaccine but also in general the fragility of the current chain of clinical trials.

Through this emergency, is it possible to look at the current clinical trial processes with new eyes? Is it possible to seize the opportunity for change and to have confidence in the possibility of their improvement? In this short article the authors wanted to give an optimistic answer to this question by pushing on the possibilities of innovation nowadays. Keywords Clinical trials; Innovation; Covid; Digital transformation. Hackensack Meridian Health, a large New Jersey network comprised of 17 hospitals, a medical school, and ambulatory care centers, executes a large research program with approximately active human subjects studies.

These included minimizing face-to-face contact among research participants and staff, allocating limited resources to handle the influx of COVID related proposals, providing human subjects protection training to the physicians and staff who were needed to run the clinical trials, adjusting bio-repository activities to meet the increased demand for samples, and disseminating all of the new regulatory and operational information to the thousands of researchers in the network.

Population knowledge and attitudes toward health insurance are important factors that facilitate health insurance coverage. National studies on these parameters are limited.

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The study was a descriptive cross-sectional community-based conducted in A-Duiem Administrative Unit, Sudan. It collected quantitative data from non-insured households and qualitative data by interviewing community leaders and conducting focus group discussions with community organizations members. Around The knowledge of non-insured community leaders and members of the community organizations was moderate. Most of the community leaders and members of the community organizations had health insurance cards. Those who were not enrolled, have limited knowledge about health insurance while almost all believe they should join it.

The study identified The study showed low health insurance coverage among families, despite their positive attitude. This is mostly attributed to poor awareness of the heads of the non-insured households about health insurance. Tail docking is usually performed on those dogs whose tail or associated structures have been injured.

A two-year-old male dog was presented Veterinary Teaching Hospital VTH with complain of injury on the tail due to bite by another dog. The injured site of the tail was contaminated with the debris on presentation and the dog was in severe pain. Amputation of the tail at the level above the injury site of the tail was taken. Care for surgery, oxytetracycline wound spray was applied on the incision site of the tail; Pen Strep and Meloxicam were given for three-days.

The suture material was removed 10th-day post-surgery and the tail stump healed uneventfully. Hence, tail amputation is the best option of treatment for severing traumatic tail and successful management of the injured tail was presented in the present case report. Keywords Dog; Injured tail; Cosmetic tail docking. Monitoring adherence to pre-exposure prophylaxis is a critical component of reaching ending the human immunodeficiency virus infection HIV epidemic goals in the US. In this mini-review, we will briefly synthesize the emerging evidence and propose a solution to ensure all patients receive the support needed to protect them from HIV acquisition.

Recently a lot of attention has been focused on fast-tracking repurposed drugs for the treatment of a novel coronavirus; severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 , the causative agent leading to the devastating coronavirus disease Covid One of the first and most well-known examples is hydroxychloroquine HCQ , which has been used for years as a treatment for malaria, rheumatoid arthritis and lupus.

HCQ was rolled out as a miracle treatment for Covid, which was inexpensive, effective and causing few side-effects.

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However, its effectiveness in treating Covid has recently been questioned leaving doctors and patients confused and desperate. Here the proposed mechanisms of action of HCQ are discussed and compared with an inexpensive, safe and effective alternative, which is derived from natural, healthy amniotic fluid.

Introduction Although the negative pressure wound therapy NPWT is a time tested method of wound preparation, the role of NPWT with instillation and dwell time NPWTi-d in decreasing the downtime of wound preparation needs to be evaluated. Materials and Methods This study was conducted in a tertiary care center, after getting informed consent and ethical clearance. NPWTi-d was done on a years-old female with no known co-morbidities admitted with infected raw area over the right below knee amputation stump and exposed bone who was not responding well to conventional wound dressing.

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NPWT was applied with the help of sterile polyurethane sponge and two tubes. The antimicrobial solution used was ionic silver solution, just enough to wet the sponge completely and up to the point when the transparent occlusive covering begins to lift. Negative pressure was applied at mmHg. The wound was bathed with ionic silver solution and it was allowed to stay in the wound for minutes, after every 2-hours of negative pressure application. This was continued for 1-week.

The dressing was opened at the end of 1-week, wound irrigated with normal saline, exudate swabs for culture taken and debrided, following which fresh NPWTi-d was applied. This was repeated for the next 3-weeks. Result By the end of third week, the wound became clean, fully covered with healthy granulation and the wound bed was ready to undergo the definitive wound cover procedure.